https://biodecode.io/articles/ Guides on analyzing your raw DNA data privately — 23andMe, AncestryDNA, VCF files, ClinVar, and genetic privacy. en-us Fri, 12 Jun 2026 00:00:00 GMT https://biodecode.io/articles/how-to-analyze-your-23andme-raw-data/ https://biodecode.io/articles/how-to-analyze-your-23andme-raw-data/ Fri, 12 Jun 2026 00:00:00 GMT Download your 23andMe raw data, understand what the file really contains, and check it for health-relevant variants — without uploading it to anyone. https://biodecode.io/articles/how-to-download-and-read-ancestrydna-raw-data/ https://biodecode.io/articles/how-to-download-and-read-ancestrydna-raw-data/ Thu, 11 Jun 2026 00:00:00 GMT Export your AncestryDNA raw data, learn what the file's columns mean, and check it against ClinVar locally — no third-party uploads required. https://biodecode.io/articles/is-it-safe-to-upload-your-dna/ https://biodecode.io/articles/is-it-safe-to-upload-your-dna/ Fri, 05 Jun 2026 00:00:00 GMT Uploading your raw DNA to a website is convenient but irreversible. Learn what the law protects, what has gone wrong, and why local analysis avoids the risk. https://biodecode.io/articles/find-pathogenic-variants-in-your-raw-dna/ https://biodecode.io/articles/find-pathogenic-variants-in-your-raw-dna/ Tue, 02 Jun 2026 00:00:00 GMT What 'pathogenic' really means, how ClinVar classifies variants, and how to check your raw DNA for flagged markers without over-interpreting the result. https://biodecode.io/articles/variant-not-found-in-clinvar-checklist/ https://biodecode.io/articles/variant-not-found-in-clinvar-checklist/ Mon, 04 May 2026 00:00:00 GMT Got no exact ClinVar match for a VCF position, rsID, or HGVS-style name? Use this non-diagnostic checklist before assuming the database or file is wrong. https://biodecode.io/articles/rsid-vs-hgvs-vs-chrom-pos-variant-identifiers/ https://biodecode.io/articles/rsid-vs-hgvs-vs-chrom-pos-variant-identifiers/ Sun, 03 May 2026 00:00:00 GMT A practical, non-diagnostic guide to matching rsID, HGVS, CHROM:POS:REF:ALT, and ClinVar identifiers when reviewing genome file rows. https://biodecode.io/articles/grch37-vs-grch38-genome-build-variant-check/ https://biodecode.io/articles/grch37-vs-grch38-genome-build-variant-check/ Thu, 30 Apr 2026 00:00:00 GMT Learn how GRCh37 vs GRCh38 affects variant lookup, where to find build clues, and why CHROM, POS, REF, and ALT should be checked before using ClinVar context. https://biodecode.io/articles/vcf-columns-explained/ https://biodecode.io/articles/vcf-columns-explained/ Thu, 30 Apr 2026 00:00:00 GMT A plain-English guide to VCF columns, using one fictional row to explain variant identity, call quality, INFO fields, and cautious ClinVar context.